Okay, it turns out that while this option allows Macromedia Freehand to run, it disables certain other apps.
Is there an easy way to enable/disable it?
Or better still, a way to enable/disable it for specific apps when they run?
EDIT: Or, is there a way to exempt an application from this setting when it is programmed? (The specific app I need it for is an opensource app programmed using Godot, OpenSCAD Graph Editor)